Who says you have to do any of those things (aside from surviving the Pyramid) to have a submittable run? Passing through enemies with Wil is very difficult and saves a minimal amount of time, the cost-benefit just isn't worth it. And if killing the vampires isn't feasible as Wil in realtime, nobody's going to blame you for using Freedan instead.
I think SDAers try too much to blur the distinction between realtime runs and TASes. Don't torture yourself to pull off unrealistic tricks with minimal benefits just because it's possible in a TAS.
I think SDAers try too much to blur the distinction between realtime runs and TASes. Don't torture yourself to pull off unrealistic tricks with minimal benefits just because it's possible in a TAS.