Quote from ph3tt:
Hi was wondering how to skip the girl who talks to you after you come back from the sewers before the golden cat?
This is a thing that only will happen if you use the old weeper route. If you use the new one which can be seen in the newer runs and in virrwards new tutorial for the game with all the newer strats, the girl will spawn at the other hatch down to the sewer.
Example of the current weeper route: http://www.twitch.tv/janmumrik/c/4737722
Virrwards tutorial:
As far as I know with the old route the way to avoid the girls convo is to be fast out of the sewer as it is time based when she will appear there(time starting from when you neutralize the last weeper), hence the sleep dart would give you a bigger window of time due to the time it takes for the weeper to fall asleep and become neutralized.